40w LaterGuide

Active ingredients: Ethinyl estradiol + desogestrel
Form: Oral tablet

Pills containing both desogestrel and ethinyl estradiol are a type of combined oral contraceptive (COC).

In some countries, COCs containing desogestrel are described as “third-generation” pills based on the type of progestin they contain. However, this classification is not used consistently worldwide. The specific hormones and doses, along with individual health conditions and risk factors, are more important when choosing a contraceptive.

Can they be used for reasons other than contraception?

Combined oral contraceptives are primarily used to prevent pregnancy, but they can also make bleeding patterns more predictable and may reduce menstrual bleeding and period pain. They may also be prescribed to manage irregular periods associated with conditions such as PCOS.

However, birth control pills do not treat irregular ovulation in order to improve the chance of pregnancy. Because they suppress ovulation while being taken, people who are currently trying to conceive may need a different evaluation or treatment.

If bleeding suddenly becomes very heavy or unexplained bleeding keeps occurring, it is important to consider the underlying cause rather than simply controlling the bleeding with the pill.

How effective are they for contraception?

Combined oral contraceptives are highly effective when taken correctly and consistently. In everyday use, late or missed pills can reduce their effectiveness.

If you miss pills, experience vomiting or severe diarrhea, or take medications that may interact with your contraceptive, check the product instructions or ask a healthcare professional what to do.

How are second- and third-generation pills different?

The main difference is the type of progestin they contain. Their contraceptive effectiveness is generally similar, but their side-effect and risk profiles can differ.

COCs containing desogestrel are associated with a higher risk of venous thromboembolism (VTE) than COCs containing levonorgestrel. Individual risk also depends on factors such as age, smoking, body weight, and personal or family history of blood clots.

Are they suitable for everyone?

Estrogen-containing combined oral contraceptives are not suitable for everyone. A history or risk of blood clots, migraine with aura, smoking and age, blood pressure, postpartum status, and certain medications can affect whether they are appropriate.

No single “generation” is best for everyone. The most appropriate contraceptive depends on your health, risk factors, and reason for taking it.