40w LaterGuide

Fertility Guide

Second-Generation Combined Oral Contraceptives – Levonorgestrel

Active ingredients: Ethinyl estradiol + levonorgestrel
Form: Oral tablet

Birth control pills containing both levonorgestrel and ethinyl estradiol are a type of combined oral contraceptive (COC).

In some countries, contraceptives containing levonorgestrel are described as “second-generation” pills based on the type of progestin they contain. However, this classification is not used consistently worldwide. When choosing a contraceptive, the specific hormones and doses, as well as individual health conditions and risk factors, are more important than the generation label.

Can they be used for reasons other than contraception?

Combined oral contraceptives are primarily used to prevent pregnancy, but they can also make bleeding patterns more predictable and may reduce menstrual bleeding and period pain. They may also be prescribed to manage irregular periods associated with conditions such as PCOS.

However, birth control pills do not treat irregular ovulation in order to improve the chance of pregnancy. Because they suppress ovulation while being taken, people who are currently trying to conceive may need a different evaluation or treatment.

If bleeding suddenly becomes very heavy or unexplained bleeding keeps occurring, the underlying cause should be considered rather than simply using the pill to control the bleeding.

How effective are they for contraception?

Combined oral contraceptives are highly effective when taken correctly and consistently. In everyday use, however, late or missed pills can reduce their effectiveness.

Take the pill according to the instructions. If you miss pills, experience vomiting or severe diarrhea, or take medications that may interact with your contraceptive, check the product instructions or ask a healthcare professional what to do.

Are they suitable for everyone?

Combined oral contraceptives containing estrogen are not suitable for everyone. A history or risk of blood clots, migraine with aura, smoking and age, blood pressure, postpartum status, and certain medications can affect whether they are appropriate.

COCs containing levonorgestrel are associated with a lower risk of venous blood clots than some COCs containing other progestins. However, estrogen-containing combined contraceptives still increase the risk of blood clots compared with not using them.